不能人为指定非等比缩放，也不能单独控制 padding 行为所有结果都由 scale 自动推导
7The signal to noise ratio is the amount of an observed effect due to the intended process compared to other “background noise”. In this case, light resulting from nucleotide addition versus other chemical reactions. Luciferase recognizes and acts on dATP in solution, creating a spurious signal unrelated to nucleotide addition, which must be accounted for during analysis. Fortunately, the modified “A” nucleotide effectively suppresses this side reaction, improving the signal to noise ratio.
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